The word inhospitable is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Plays In The Letters inhospitable
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Seven Letter Word Alert: (88 words)
abolish, absinth, albinos, albites, alibies, alpines, aplites, apostle, astilbe, baptise, bastion, benthal, benthos, betoils, biolite, biolith, biotins, biphase, biplane, bipoles, boniest, elastin, elation, elision, entails, epsilon, ethanol, halites, haplite, hatpins, hipbone, histone, hobnail, holiest, hoplite, hostile, hotline, inhabit, inhales, inosite, iolites, iphones, isolate, leantos, leptons, lesbian, liaison, libates, lionets, lionise, loathes, nailset, nepotal, niobate, niobite, noblest, notable, obtains, oiliest, opaline, opiates, panties, patines, pentail, phablet, phenols, phobias, phonies, pianist, pilates, pinhole, pinitol, pintail, planets, plebian, pleions, potable, salient, sealion, spaniel, tailpin, taphole, teashop, thiones, tiepins, toenail, topline, topsail