The word wholeheartedly is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (75 words)
alerted, alertly, allowed, alloyed, altered, deathly, deerlet, delator, delayer, deleter, dewater, drywall, drywell, dweller, dyeware, earthed, earthly, elderly, eyehole, eyewall, eyewear, hayweed, healder, healthy, hearted, heather, hothead, hydrate, lathery, layered, leadeth, leather, leeward, leotard, loathed, loather, loathly, lowered, loyaler, lyrated, oarweed, oreweed, rathole, reallot, reallow, redealt, related, relayed, retally, tallowy, tallyho, tarweed, thready, tollway, toweled, towered, trawled, treadle, trolled, trolley, tweedle, walleye, watered, wealthy, weather, wheedle, wheeled, wheeler, whereat, whereto, whether, whorled, worldly, wreathe, yodeler