The word synthetically is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters synthetically
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Seven Letter Word Alert: (82 words)
acetyls, achiest, aitches, alethic, anthill, atheist, cantles, castile, cattily, cellist, chalets, chantey, chasten, chattel, clayish, cleanly, clients, cyanise, cyanite, cystine, elastic, elastin, entails, etchant, ethical, ethnics, ethynyl, halites, hastily, helical, hellcat, hyaline, hyalite, inhales, install, instate, instyle, laciest, lancets, latches, latency, latents, latites, lattice, lentils, lichens, lintels, lithely, lynches, nailset, nastily, nattily, nictate, saintly, salient, saltily, satchel, satiety, scantly, shellac, snatchy, snitchy, stately, statice, stealth, stenchy, stencil, stylate, tacitly, tactile, talents, tallest, tallies, tallish, tastily, tenthly, testacy, testily, tetanic, thistle, thistly, yachtie