The word straightjacket is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 34
Highest Scoring Words With Friends™ Play In The Letters straightjacket
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Seven Letter Word Alert: (93 words)
acaters, achiest, agarics, agatise, agitate, aigrets, aitches, artiest, atheist, atresia, attache, attacks, attires, attract, attrist, attrite, cagiest, cakiest, cartage, cashier, cattier, charges, chaster, chatter, cithers, citrate, cristae, eartags, gaiters, gastric, gathers, hackers, hastate, hastier, hatrack, hatters, hijacks, hitters, iratest, jackets, jitters, karites, karstic, raciest, rackets, ratchet, rattish, regatta, resight, restack, restick, retacks, richest, rickets, ricksha, satiate, scatter, seajack, shakier, shatter, shitake, sighter, skitter, stacker, stagier, statice, sticker, stretch, striate, tackers, tackier, targets, tartest, tartish, tastier, tatters, tattier, teacart, teargas, thicker, thicket, threats, tickers, tickets, tighter, tithers, titrate, titters, trachea, traject, triages, trijets, trisect