The word responsibly is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (38 words)
bipoles, boilers, bossier, bossily, boysier, byliner, bylines, byssine, epsilon, insoles, leprosy, lesions, lioness, lispers, lossier, ospreys, persons, pinless, pleions, preboil, prisons, proline, pronely, pyrones, reboils, resoils, respins, ribless, riboses, seniors, sensory, slopers, snipers, soberly, spinels, spinose, splines, spoiler