The word dodecahedrons is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (95 words)
acerose, achenes, acnodes, addends, adhered, adheres, adhorns, adorned, anchors, archons, arsheen, candors, canoers, careens, cheddar, chooser, coarsen, cohered, coheres, condors, corands, cordons, corneas, coronas, crashed, creased, crooned, dancers, danders, deacons, deadend, deadens, deashed, decades, decanes, decares, decoded, decoder, decodes, dehorns, deodand, deodars, descend, deshade, desnood, dodders, doodads, dreaded, dresden, echoers, encased, encoded, encoder, encodes, encored, encores, endears, endorse, hadrons, handers, hardens, headers, headons, hearsed, hoarded, honored, honoree, necrose, nodders, onshore, racoons, ranched, ranches, reached, reaches, readded, recaned, recanes, rechose, recoded, recodes, reddens, redhead, rehoned, rehones, reshoed, roached, roaches, rodeoed, sarcode, scorned, sheared, shedded, shedder, snooded