The word depressants is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 16
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (82 words)
adepter, aptness, asepses, asperse, assents, asserts, dearest, densest, departs, depress, deserts, dessert, dresses, earnest, eastern, endears, ensears, entraps, nearest, nesters, panders, panters, parents, passers, pasters, pedants, pesters, petards, predate, present, presets, pressed, presses, pretans, pretend, reasted, redates, redness, redtape, renests, repaste, repasts, repeats, repents, resands, reseats, resends, resents, resnaps, respade, respans, resteps, retaped, retapes, sadness, sanders, sateens, seaters, sedater, sedates, senates, senders, sensate, serapes, serpent, spaders, sparest, speared, spender, spreads, standee, stander, sterane, sterned, strands, tapered, tasered, teasers, tenders, trepans, tressed, tresses