The word depressant is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 15
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (74 words)
adepter, aptness, asperse, dearest, densest, departs, depress, deserts, dessert, earnest, eastern, endears, ensears, entraps, nearest, nesters, panders, panters, parents, pasters, pedants, pesters, petards, predate, present, presets, pressed, pretans, pretend, reasted, redates, redness, redtape, renests, repaste, repasts, repeats, repents, resands, reseats, resends, resents, resnaps, respade, respans, resteps, retaped, retapes, sanders, sateens, seaters, sedater, sedates, senates, senders, sensate, serapes, serpent, spaders, sparest, speared, spender, spreads, standee, stander, sterane, sterned, strands, tapered, tasered, teasers, tenders, trepans, tressed