The word cantaloupes is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (75 words)
acouple, actuals, acuates, alecost, alecups, anapest, apostle, canapes, cantles, canulae, canulas, caplets, capstan, capsule, catnaps, cleanup, closeup, coastal, consult, counsel, couples, couplet, cupolas, cuspate, eluants, enclasp, lactase, lactone, lactose, lacunae, lancets, leantos, leptons, locates, lunates, nepotal, nutcase, octanes, octuple, opulent, outleap, outpace, outplan, outspan, paenula, palaces, palates, peanuts, peasant, penults, placate, planeta, planets, plateau, plutons, polecat, pounces, pulsate, saltpan, scapula, sealant, spatula, specula, sulcate, sultana, teacups, toecaps, toucans, uncapes, unclasp, unclose, unclots, unlaces, upscale, upslant