The word unpropitiously is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Play In The Letters unpropitiously
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Seven Letter Word Alert: (56 words)
lotions, nitrous, nitryls, noisily, nostril, options, outpour, outruns, outspin, outspun, pinitol, piously, plosion, plutons, polypus, poplins, portion, potions, poultry, protons, pulpits, purlins, purloin, pursuit, pylorus, riotous, ripstop, ruinous, rustily, sirloin, slipout, sootily, soppily, spinout, splitup, sporont, stipply, stonily, stroppy, stylion, support, tipsily, topsoil, topspin, topspun, torsion, trypsin, turnips, unsilty, unsplit, unstrip, untruly, uproots, upsilon, upturns, youpons