The word septillions is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 17
Highest Scoring Words With Friends™ Plays In The Letters septillions
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Seven Letter Word Alert: (47 words)
elision, enlists, epsilon, illites, illness, inosite, insoles, insteps, instill, iolites, ionises, isospin, lentils, leptons, lesions, lintels, lioness, lionets, lionise, lipless, listens, nosiest, oiliest, pillion, pinitol, pinless, pistils, pistols, pistons, pitless, pleions, pollens, postils, silents, spinels, spinets, spinose, splines, splints, stepson, stollen, tiepins, tinsels, tipless, tonsils, topless, topline