The word preoccupation is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 27
Highest Scoring Words With Friends™ Play In The Letters preoccupation
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Seven Letter Word Alert: (83 words)
account, aconite, appoint, apricot, auction, cantrip, caption, capture, cartoon, caution, centaur, centric, certain, coactor, cocaine, coconut, cocopan, conceit, concept, concert, contour, coppice, cornice, coronet, counter, crappie, crouton, cuprite, curtain, ecotour, ectopia, ectopic, enactor, epicarp, erotica, nepotic, oceanic, oncotic, operant, oration, otarine, outcrop, outearn, outpace, outpipe, outrace, painter, peccant, pertain, petunia, picante, picrate, picture, pointer, popcorn, porcine, porotic, portico, portion, pouncer, poutier, poutine, practic, precoat, pronate, prootic, propane, propine, protean, protein, puritan, raccoon, rainout, recount, reinput, repaint, repoint, routine, toprope, trounce, uncrate, urinate, utopian