The word orthopaedic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters orthopaedic
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Seven Letter Word Alert: (54 words)
adopter, apricot, carotid, cathode, chaired, chapter, chariot, charted, chirped, choroid, coopted, cordate, diopter, dioptre, ditcher, ectopia, edaphic, erotica, hardtop, haricot, hepatic, ootheca, opiated, optrode, parched, parotid, patched, peridot, photoed, picrate, pirated, pitched, pitcher, pithead, poached, poacher, pooched, porched, porotic, portico, pothead, potiche, precoat, predict, prootic, readopt, repatch, repitch, roached, toparch, torched, torpedo, trooped, trophic