The word operationally is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Play In The Letters operationally
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Seven Letter Word Alert: (83 words)
aeolian, aileron, airplay, alertly, allayer, analyte, aplenty, apteria, arylate, atropia, elation, entropy, ineptly, inertly, inlayer, irately, lateral, latrine, literal, loonier, loopier, loyaler, nepotal, opaline, operant, oration, otarine, painter, partial, patella, patinae, patrial, payroll, penalty, pentail, pertain, pillory, plainer, plainly, planeta, plantar, planter, platoon, playlet, plenary, pointer, polarly, polaron, politer, portion, praline, prelaty, proline, pronate, pronely, protean, protein, pteryla, ptyalin, ratline, reality, reallot, reliant, repaint, repayal, repilot, replait, replant, repoint, retally, retinal, retinol, tallier, tearily, toenail, tonally, topiary, topline, toprail, trenail, tripole, trolley, trollop