The word masochistically is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 30
Highest Scoring Words With Friends™ Play In The Letters masochistically
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Seven Letter Word Alert: (69 words)
acclaim, accloys, accosts, acholia, atomics, calicos, catcall, chamois, chaotic, chyloma, chymics, chymist, classic, clastic, clayish, clitics, cloacal, cloacas, coastal, colitis, coltish, comical, cyathia, cyclism, cyclist, cystoma, cytomas, cytosis, hastily, ischiac, ischial, italics, loathly, mascots, miscall, miscast, mislays, mistily, mitosis, moistly, mosaics, mycolic, mycosis, mycotic, myotics, mystics, salamis, saltily, scatoma, sciatic, scillas, scythic, shallot, silicas, sitcoms, slaloms, slimily, socials, solicit, somatic, somitic, stoical, stomach, stylish, tallish, tallyho, thalami, tylosis, yashmac