The word irreproachable is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Play In The Letters irreproachable
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Seven Letter Word Alert: (60 words)
achiral, acholia, aerobic, airable, airhole, archeal, areolae, areolar, barrier, belcher, bipolar, brachia, brioche, broiler, caliber, calibre, caliper, calorie, capable, caroler, carrier, cerebra, charier, cheaper, cheerio, chirper, cholera, chorale, clearer, coalier, coherer, crabier, earache, earlier, earlobe, epochal, haircap, harelip, hoarier, laborer, leacher, parable, parboil, percher, phobiac, piercer, placebo, poacher, polaric, preboil, prerace, railcar, reacher, rebrace, reperch, replace, replica, replier, reprice, reprobe