The word hypothesising is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters hypothesising
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Seven Letter Word Alert: (58 words)
egoists, eighths, gipsies, gneissy, gossipy, gothish, gypsies, heights, highest, hightop, hipness, hissing, histone, hogties, honesty, hosting, hotness, hyphens, ignites, ingests, inosite, insight, insteps, ionises, iphones, isohyet, isospin, isotype, nightie, nosiest, phoneys, phonies, pigeons, pingoes, pistons, pithing, pitying, poising, posting, pythons, shoeing, signets, siphons, spigots, spinets, spinose, spiting, sponges, stepson, stogeys, stogies, stonish, syphons, thiones, tiepins, tossing, yessing, yoginis