The word holometabolous is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters holometabolous
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Seven Letter Word Alert: (36 words)
ablutes, alumels, amulets, ballets, ballots, bemauls, boohoos, boomlet, bullate, bullets, embolus, hamlets, humbles, loathes, lobules, losable, mallets, malleus, maltose, moolahs, mullets, mutable, osteoma, outsell, outsole, seaboot, sellout, shallot, shamble, soluble, stumble, taboule, thallus, toluole, toluols, tumbles