The word cosmetically is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Plays In The Letters cosmetically
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Seven Letter Word Alert: (71 words)
accites, accloys, acetyls, acolyte, alecost, alltime, aloetic, ascetic, atomics, atomise, cacolet, calcite, calicle, calicos, callose, calmest, calomel, calyces, castile, cecally, cellist, celosia, clastic, climate, closely, coalise, coalite, coeliac, collate, collect, collies, cometic, comical, cotylae, cotyles, cyclase, cyclise, cyclism, cyclist, cystoma, cytomas, elastic, emacity, isolate, laciest, lactose, laytime, locales, locates, malices, mallets, maltose, meatily, metical, micella, millets, miscall, mistell, moistly, motleys, mycelia, mycetal, mycolic, mycotic, myeloic, myotics, saltily, society, somatic, stoical, tallies