The word astonishment is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters astonishment
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Seven Letter Word Alert: (56 words)
amnions, animose, anoints, anthems, ashiest, atheism, atheist, atomise, haemins, hastens, histone, homiest, hotness, inmates, inseams, instant, instate, intents, intones, mannish, mansion, mention, messiah, misseat, mitoses, mittens, moisten, montane, nations, nonmate, nonmeat, noseans, nosiest, notists, seamost, seitans, sestina, siennas, smitten, somites, sonnets, stamens, statins, station, statism, stetson, stomate, stomies, stonish, tannest, taoists, tenants, tension, theisms, theists, thiones