The word reprehensibly is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (37 words)
beeline, beepers, beerish, berries, bleeper, byliner, bylines, helpers, leerier, peelers, phenyls, phrensy, preener, reelers, reheels, rehires, reliers, relines, repeels, repiles, repiner, repines, replier, replies, reprise, rerinse, reshine, respire, ribeyes, seepier, serener, sheerer, sheerly, sleeper, sneerer, yeelins, yelpers