The word realistically is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (77 words)
acaters, acatery, acetyls, acylase, acylate, aerials, aircell, airiest, alertly, allayer, allelic, allstar, article, arylate, astylar, atresia, callers, cartels, castile, cellars, cellist, ciliary, ciliate, clarets, clarity, clayier, clearly, clerisy, cristae, crystal, eclairs, elastic, elicits, icetray, illites, irately, irisate, italics, laciest, lactase, lacteal, laicise, lariats, lateral, literal, lyrical, raciest, rallies, realist, reality, recalls, recital, retails, retally, retills, rillets, saltier, saltily, satiric, scalier, scarily, scarlet, scleral, silicle, sillier, siltier, slatier, stellar, stiller, stylier, tallier, tallies, tearily, tillers, treacly, trellis, trysail