The word prosthetic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 18
Highest Scoring Words With Friends™ Play In The Letters prosthetic
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Seven Letter Word Alert: (45 words)
chipset, ciphers, cithers, coheirs, copiers, cotters, erotics, heroics, hitters, hospice, ostrich, pettish, pitcher, pitches, poetics, porches, pothers, potiche, potters, potties, protect, protest, protist, repitch, rhotics, richest, ropiest, rosehip, shitpot, spheric, spotter, stretch, strophe, thorite, tipster, tiptoer, tiptoes, tithers, torches, triceps, tricots, trisect, trophic, tropics, tropist