The word macromolecules is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 29
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (81 words)
accrues, accurse, accuser, acerose, acerous, acomous, aerosol, allures, alumels, amerces, amorous, areoles, aureole, callers, callose, callous, calomel, carouse, cellars, cereals, clammer, clamors, clamour, cleomes, closure, coalers, coeloms, coerces, collars, colours, coolers, corolla, coulees, creoles, creosol, cureall, emulsor, escolar, euclase, laurels, leucoma, locales, locules, macules, malleus, maulers, measure, mollusc, morales, morulas, mucosae, mucosal, mullers, occluse, occular, ocellar, oculars, oolemma, oracles, oscular, racemes, recalls, reclose, recluse, recoals, recusal, relaces, rescale, roseola, ruesome, sclerae, scleral, searoom, secular, serumal, slammer, slummer, smaller, smeller, solacer, urosome