The word extrapolation is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters extrapolation
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Seven Letter Word Alert: (82 words)
aeolian, aileron, apatite, apteria, atropia, elation, explain, explant, exploit, latrine, laxator, loonier, loopier, nattier, nepotal, nitrate, notator, opaline, operant, oration, otarine, otolite, oxalate, oxolane, painter, partial, patient, patinae, patrial, patriot, pattern, pentail, pertain, plainer, planeta, plantar, planter, platoon, platter, plotter, pointer, polaron, politer, portent, portion, portlet, praline, prattle, proline, pronate, protean, protein, ratline, rattail, rattoon, relaxin, reliant, repaint, repilot, replait, replant, repoint, retinal, retinol, retotal, rootlet, tanapox, taproot, tartpan, tertial, tiptoer, toenail, tootler, topline, toprail, tornote, trenail, triaxle, triaxon, triplet, tripole, triptan