The word destructing is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (68 words)
cinders, cistern, cittern, credits, cretins, cringed, cringes, crudest, cruised, crusted, cursing, cutters, cutting, decrust, dentist, directs, discern, ducting, dunites, dustier, dusting, educing, encrust, entrust, gritted, grunted, gunters, gustier, gutsier, gutters, incrust, inducer, induces, inducts, insured, intrude, intrust, nutsier, nutters, nuttier, reducts, rescind, resting, retints, reusing, rudites, rusting, rutting, setting, stinger, stinted, student, studier, stunted, stunter, testing, tinders, tinters, trident, trisect, trudgen, trudges, trusted, uncited, undrest, uniters, untired, untried