The word crossbreeding is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 23
Highest Scoring Words With Friends™ Play In The Letters crossbreeding
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Seven Letter Word Alert: (156 words)
bedress, bedsore, benders, bendier, berried, berries, besides, bigness, binders, bingers, binodes, birders, bodices, borders, boreens, borings, bossier, bossing, bridges, bringer, censers, censors, cerises, ceroids, cession, cinders, codeine, codgers, codings, cognise, coiners, cording, coreign, corners, cornier, cosigns, cosines, cringed, cringer, cringes, cronies, crosier, crossed, crosser, deboner, debones, decrier, decries, deicers, deniers, denoise, derbies, dernier, derries, designs, desirer, desires, digress, diocese, discern, disrobe, dossier, dresser, ebonics, ebonies, encoder, encodes, encored, encores, endorse, engross, enrobed, enrober, enrobes, eroding, genders, generic, genesis, girders, girners, greisen, grinder, grocers, groined, grossed, grosser, iceberg, ignored, ignores, inbreds, inbreed, indorse, ingress, ironers, necrose, negroes, negroid, nerdier, nordics, obscene, rebegin, rebinds, rebonds, rebored, rebores, recodes, recoins, records, recross, redness, redoing, redress, redries, regions, regress, regrind, reigned, reigner, renders, rerinse, rescind, rescore, resends, resider, resides, resigns, resorbs, riboses, ringers, rinsers, rosined, scorers, scoring, scorned, scorner, screeds, screens, scribed, scriber, scribes, secerns, seconds, sedgier, seeding, senders, seniors, signees, signers, signors, sincere, singers, snorers, sobered, soberer, sodgers, soirees