The word butterscotches is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (95 words)
becrust, bescour, besorts, betroth, betters, borscht, botcher, botches, bothers, brushes, busters, butcher, butters, cherubs, chouser, chouses, coerces, coheres, corsets, cotters, couches, courses, creches, cresset, crochet, crushes, curette, cutters, echoers, escorts, estrous, etchers, herbose, herbous, heteros, hottest, hottubs, obscure, obtuser, oestrus, ousters, outbets, outsees, outsets, rechose, recuses, rehouse, rescues, resects, reshoes, retches, retests, retouch, rosette, scouter, screech, secrets, sectors, secures, setters, sherbet, shouter, shutter, soccers, sorbets, sources, sourest, stereos, stouter, streets, stretch, strobes, stuccos, stutter, subsect, subsort, subtest, subtree, succors, sucrose, tersest, testers, tethers, thereto, thrusts, torches, toruses, totters, toucher, touches, touters, trochee, trustee, turbots, tutoree