The word saccharine is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters saccharine
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Seven Letter Word Alert: (20 words)
anarchs, archaic, archean, arcsine, arsenic, arshine, cachers, cancers, carinae, carnies, cashier, chainer, chances, chancre, cinches, hernias, inchers, inreach, ranches, rechain