The word reputability is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (37 words)
ability, abutter, battery, battier, battler, bilayer, biliary, bitpart, bitrate, bittier, brittle, buttery, irately, liberty, petabit, pettily, platter, prattle, prelaty, pteryla, puberty, puttier, ratbite, reality, rebuilt, replait, tearily, terabit, tertial, titular, triable, tribute, triplet, typebar, uralite, utility, utterly