The word paleocortical is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 24
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (72 words)
aircell, aircool, aloetic, apricot, apteria, article, atropia, cacolet, calcite, calicle, caliper, caloric, calorie, caltrap, caltrop, capital, capitol, carpool, catcall, circlet, clipart, cloacae, cloacal, coactor, coalier, coalite, coalpit, coaltar, coeliac, collate, collect, collier, copilot, corolla, ectopia, ectopic, erotica, icecool, lacteal, lateral, literal, locator, loopier, ocellar, optical, partial, patella, patrial, piccolo, picrate, placate, plicate, polaric, polecat, politer, porotic, portico, practic, precoat, precool, prootic, reallot, recital, repilot, replait, replica, tallier, tapioca, topical, toprail, tripole, trollop