The word nonoperational is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Plays In The Letters nonoperational
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Seven Letter Word Alert: (65 words)
aeolian, aileron, alanine, antenna, antlion, apteria, atropia, elation, entrain, intoner, lantern, latrine, loonier, loopier, nepotal, noniron, nonlate, nonleap, nonliar, nonreal, nonriot, onliner, opaline, operant, oration, otarine, painter, partial, patinae, patrial, pennant, pentail, pertain, pinnate, plainer, planeta, planner, plantar, planter, platoon, pointer, polaron, politer, pontine, pontoon, portion, praline, proline, pronate, protean, protein, ratline, reliant, repaint, repilot, replait, replant, repoint, retinal, retinol, toenail, topline, toprail, trenail, tripole