The word nightclothes is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 23
Highest Scoring Words With Friends™ Play In The Letters nightclothes
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Seven Letter Word Alert: (61 words)
choline, clients, closing, clothes, cognise, coltish, congest, contest, costing, echoing, egotist, eighths, elogist, eloigns, english, enlight, etching, ethnics, ghettos, glisten, glottis, gnostic, gothics, gothish, gothite, heights, highest, histone, hitches, hogties, holiest, hostile, hosting, hotline, leching, lection, legions, lengths, letting, lichens, lighten, lingoes, lionets, longest, longish, notches, notices, section, setting, shingle, shoeing, singlet, sleight, stencil, testing, thiones, thistle, tighten, tingles, toilets, tonight