The word monohydrate is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters monohydrate
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Seven Letter Word Alert: (29 words)
another, anymore, doorman, doormat, doormen, dormant, draymen, harmony, honored, hormone, hydrant, hydrate, hydroma, manhood, menorah, moorhen, mordant, mordent, motored, odorant, roadmen, tearoom, theonym, thorned, thready, throned, tonearm, tornado, yardmen