The word macrocephalic is playable in Words With Friends™, but 1 blank substituting for the letter 'c' is required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 27
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (57 words)
acclaim, achiral, acholia, airhole, amphora, archaic, archeal, armhole, cacemia, cacemic, caliche, caliper, caloric, calorie, camphor, campier, caramel, ceramic, chalice, chimera, choicer, choleic, cholera, chomper, chorale, chromel, chromic, claimer, clamper, cloacae, coalier, cochair, cochlea, coeliac, comical, compare, compile, crimple, epochal, haircap, harelip, impaler, impeach, implore, lempira, loamier, mailcar, miracle, morphic, palmier, poacher, polaric, polemic, racemic, reclaim, reclamp, replica