The word groundlessness is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (91 words)
delouse, deluges, dengues, dogless, dousers, dresses, duelers, dungeon, egoless, eldress, eluders, endless, endogen, endorse, endures, engross, ensouls, ensured, ensures, gelders, genders, genuses, glossed, glosser, glosses, godless, goldens, gourdes, grossed, grosses, grounds, groused, grouses, guerdon, guessed, guesser, guesses, guldens, gunless, gunners, ledgers, legends, lenders, lessens, lessons, lessors, lodgers, longrun, lounged, lounger, lounges, negroes, neurons, nodules, nondrug, nonuser, oldness, oneness, redness, regloss, reglued, reglues, regulon, relodge, resends, resoled, resoles, resound, rodless, roundel, runnels, senders, sensors, sledges, slender, sludges, snudges, sodgers, sodless, solders, sonless, sounder, sudsers, sundogs, sunless, surgeon, undergo, undoers, undress, unreels, useless