The word encephaloceles is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 28
Highest Scoring Words With Friends™ Play In The Letters encephaloceles
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Seven Letter Word Alert: (34 words)
achenes, alpeens, callose, cancels, chancel, chances, chapels, cheapen, cheapos, cleanse, cloches, coaches, cochlea, conceal, conches, echelon, enclasp, enclose, enolase, epochal, escapee, leaches, leeches, locales, peaches, pencase, phenols, poaches, pollens, scalene, scallop, scalpel, shellac, spelean