The word desiccation is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (63 words)
accents, accited, accites, acnodes, aconite, actinic, actions, adonise, anodise, ascetic, atonics, candies, cations, coacted, coasted, cocaine, codices, coedits, conceit, concise, conidia, dacites, deacons, decants, decocts, deictic, deistic, descant, destain, detains, diciest, diction, dietics, dioecic, discant, donates, edition, eosinic, iconist, incased, incised, incited, incites, indices, indicts, indites, inosite, instead, iodines, iodites, ionised, nicosia, noticed, notices, oceanic, octadic, octanes, sainted, sciatic, sconced, section, stained, tacnode