The word counteractive is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters counteractive
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Seven Letter Word Alert: (87 words)
account, accrete, acetone, aconite, activer, arenite, auction, carvone, cattier, caution, centaur, centric, certain, citator, citrate, cittern, cocaine, concave, conceit, concert, contact, convect, convert, convict, cornett, cornice, coterie, counter, coveter, crevice, cuneate, curette, curtain, cutover, cutrate, eccrine, enactor, enteric, enticer, entreat, erotica, etaerio, evictor, evitate, evocate, incurve, iterate, nattier, nictate, nitrate, nuttier, oceanic, otarine, outearn, outrace, outrant, outrate, outrave, overact, overate, overcut, overeat, rainout, recount, reenact, reunite, revoice, ricotta, routine, tantric, taunter, tentier, ternate, tetanic, trainee, triaene, trounce, tutoree, uncover, uncrate, unerect, unrivet, urinate, uterine, vaccine, venture, veteran