The word cleistogamic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 24
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (59 words)
accites, aiglets, alecost, aloetic, ascetic, atomics, atomise, cacolet, cagiest, calcite, calicos, calmest, castile, catelog, celosia, ciliate, clastic, climate, clitics, coalise, coalite, coeliac, colitis, cometic, comical, egotism, elastic, elicits, elitism, elogist, gametic, gamiest, gelatos, gliomas, goalies, icicles, imagoes, iolites, isolate, italics, laciest, lactose, laicise, ligates, locates, malices, maltose, meiotic, metical, miscite, oiliest, oligist, sciatic, semilog, sigmate, solicit, somatic, somitic, stoical