The word antisyphilitic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Play In The Letters antisyphilitic
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Seven Letter Word Alert: (41 words)
apishly, aplitic, caliphs, catnips, cattily, chitlin, clayish, haptics, hastily, hatpins, inclasp, initial, ischial, italics, nastily, nattily, pachisi, pianist, pintail, pithily, plastic, pliancy, ptyalin, saintly, scantly, shinily, snatchy, snitchy, spicily, spinach, splatch, styptic, sylphic, tacitly, tailpin, tastily, thistly, tipcats, tipsily, titanic, typical