The word throatiest is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 12
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (29 words)
artiest, atheist, attires, attrist, attrite, earshot, hastier, hatters, hitters, hottest, iratest, rattish, retoast, rotates, shatter, striate, tartest, tartish, tastier, tatters, tattier, thorite, threats, throats, tithers, titrate, titters, toaster, totters