The word quarrelsome is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (27 words)
areoles, armours, arouser, aureole, emulsor, erasure, marquee, marques, maulers, measure, morales, morulas, quarrel, realers, reamers, rearose, remorse, resumer, roamers, ruesome, sequela, serumal, smearer, squalor, squarer, surreal, uromere