The word polytheistic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 23
Highest Scoring Words With Friends™ Play In The Letters polytheistic
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Seven Letter Word Alert: (48 words)
chilies, chipset, clothes, colitis, coltish, copyist, cotyles, cotypes, elicits, elitist, holiest, hoplite, hospice, hostile, iolites, isohyet, isotype, oiliest, pelitic, pettily, pettish, pietist, pitches, pithily, poetics, polices, politic, potiche, potties, pottles, shitpot, society, solicit, spicily, spittle, splotch, spotlit, spyhole, stipite, styptic, sylphic, testily, thistle, thistly, tipsily, tiptoes, toilets, tylotes