The word federalism is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 18
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (49 words)
admires, aediles, dealers, dearies, defamer, defames, defiers, defiler, defiles, defleas, delimes, derails, deslime, dialers, emailed, emerald, faeries, fardels, federal, females, fielder, flamers, freesia, leaders, leafier, limeade, mailers, mealier, misdeal, misfeed, mislead, misread, readies, readmes, realise, realism, redeals, redials, refiled, refiles, refilms, reflies, reliefs, remails, sealife, seamier, seriema, sidearm, smeared