The word encephalopathy is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 31
Highest Scoring Words With Friends™ Play In The Letters encephalopathy
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Seven Letter Word Alert: (51 words)
acetone, acolyte, acylate, analyte, aplenty, apocyte, chantey, chaplet, cheapen, cheaply, cheetah, chelate, cholate, claypan, cotylae, cyanate, echelon, ecotype, enocyte, enolate, eophyte, epochal, ethanol, halcyon, healthy, heathen, heeltap, heptane, heptyne, lactone, latency, naphtha, neocyte, neotype, nepotal, paleate, palpate, papalty, penalty, peptone, phenate, phthaly, placate, planeta, playact, playpen, polecat, potency, potheen, tachyon, taphole