The word desalinate is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 13
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (33 words)
aediles, aliased, aniseed, dealate, delates, delints, denials, dentals, dentils, destain, destine, details, detains, dilates, elastin, entails, instead, lateens, leanest, lenited, lenites, lineate, linseed, nailset, nestled, sainted, salient, sealant, slanted, snailed, stained, standee, tensile