The word denigrative is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (69 words)
angered, arenite, avenged, avenger, averted, darting, deaving, denarii, deraign, derange, detrain, deviant, deviate, dietine, dieting, dingier, diverge, diviner, dragnet, drivein, driving, editing, engrave, enraged, evading, evident, eviting, grained, granite, granted, grantee, greaten, grenade, grieved, ignited, igniter, inditer, inertia, ingrate, integer, invader, invited, invitee, inviter, negated, nitride, raiding, reading, reagent, reaving, reeving, reigned, riveted, tangier, tearing, tiering, tradein, trading, trained, trainee, treeing, triaene, vearing, veering, veinier, veteran, vinegar, vintage, vitrine