The word cardiomegaly is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 24
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (65 words)
academy, acridly, admiral, alamode, alarmed, already, amyloid, armload, caldera, calorie, camelid, caramel, carload, caroled, claimed, claimer, clayier, coalier, comrade, cordage, cordial, crayola, damager, daycare, decalog, decimal, declaim, decrial, diagram, diorama, dormice, drayage, earldom, earmold, geoidal, glacier, gloamed, gloried, godlier, gracile, grimace, imagery, loamier, magical, mailcar, mayoral, medical, megarad, melodic, midyear, miracle, moldier, myalgia, myalgic, mycelia, myeloic, myeloid, oracled, radical, radicel, radicle, readily, reclaim, regalia, yardage