The word astrophysics is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters astrophysics
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Seven Letter Word Alert: (39 words)
apricot, assorts, atrophy, captors, carhops, casspir, castors, chariot, charity, chassis, copyist, costars, cytosis, haptics, haricot, harpist, history, isopach, opacity, ostrich, pastors, physics, prosaic, psychos, racists, rapists, raspish, rhotics, schists, scissor, scorias, scripts, sophtas, spastic, starchy, toparch, topiary, trophic, tropics